Cancer Virotherapy and Immunotherapy

Ramon Alemany Bonastre

CLINICAL RESEARCHERS (R2)
  • Miriam Bazan Peregrino
POSTDOCTORAL RESEARCHERS (R2)
  • Marcel Costa Garcia
PREDOCTORAL RESEARCHERS (R1)
  • Martí Farrera Sal
  • Laura Moya Borrego
SCIENTIFIC SUPPORT
  • Rafael Moreno Olié
  • Silvia Torres Manjon
  • Paz Moreno Serrano
Cancer
Oncobell

Scientific production

5

PAPERS

Impact factor: 28,526

1 PUBLICATIONS IN FIRST DECILE

4 PUBLICATIONS IN FIRST QUARTILE

Selected publications

  • Ruano, David; Lopez-Martin, Jose A.; Moreno, Lucas; Lassaletta, Alvaro; Bautista, Francisco; Andion, Maitane; Hernandez, Carmen; Gonzalez-Murillo, Africa; Melen, Gustavo; Alemany, Ramon; Madero, Luis; Garcia-Castro, Javier; Ramirez, Manuel. First-in-Human, First-in-Child Trial of Autologous MSCs Carrying the Oncolytic Virus Icovir-5 in Patients with Advanced Tumors. MOLECULAR THERAPY. 10.1016/j.ymthe.2020.01.019
  • Farrera-Sal M., Fillat C., Alemany R.. Effect of transgene location, transcriptional control elements and transgene features in armed oncolytic adenoviruses. CANCERS. 10.3390/cancers12041034
  • Farrera-Sal, Marti; de Sostoa, Jana; Nunez-Manchon, Estela; Moreno, Rafael; Fillat, Cristina; Bazan-Peregrino, Miriam; Alemany, Ramon. Arming Oncolytic Adenoviruses: Effect of Insertion Site and Splice Acceptor on Transgene Expression and Viral Fitness. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 10.3390/ijms21145158
  • Barlabé P., Sostoa J.d., Fajardo C.A., Alemany R., Moreno R.. Enhanced antitumor efficacy of an oncolytic adenovirus armed with an EGFR-targeted BiTE using menstrual blood-derived mesenchymal stem cells as carriers. CANCER GENE THERAPY. 10.1038/s41417-019-0110-1
  • Sendra, Luis; Miguel, Antonio; Navarro-Plaza, M. Carmen; Herrero, Maria Jose; de la Higuera, Jose; Chafer-Pericas, Consuelo; Aznar, Elena; Marcos, M. Dolores; Martinez-Manez, Ramon; Rojas, Luis Alfonso; Alemany, Ramon; Alino, Salvador F.. Gold Nanoparticle-Assisted Virus Formation by Means of the Delivery of an Oncolytic Adenovirus Genome. NANOMATERIALS. 10.3390/nano10061183

Research highlights

PROJECTS

2 Ongoing projects

2 Ongoing clinical trials

PUBLISHED WORKS

1 Defended thesis

INNOVATION

1 Patents

1 Spin-off
 

Selected projects

  • Adenovirus oncolíticos protegidos frente an anticuerpos y armados con transgenes para eliminar el estroma y estimular respuestas inmunes antitumorales.
  • Ayudas para contratos predoctorales para la formación de doctores 2018 (2019 – 2023) PI: ALEMANY BONASTRE, RAMON. Funder: MINISTERIO DE EDUCACION Y CIENCIA.
  • Estudios traslacionales en relación al proyecto: “phase II trial of durvalumab (medi4736) plus tremelimumab with concurrent radiotherapy in patients with localized muscle invasive bladder cancer treated with a selective bladder preservation approach” (2019 – 2020) PI: ALEMANY BONASTRE, RAMON. Funder ref.: CI-001/19.
  • Medició de l’activitat antitumoral de VCN-01 en models ortotòpics TP11 de ratolí (2017 – 2020) PI: ALEMANY BONASTRE, RAMON. Funder: VCN BIOSCIENCES, S.L..