Hereditary cancer

Gabriel Capella Munar/ Conxi Lázaro Garcia

PRINCIPAL INVESTIGATORS
  • Joan Maria Brunet Vidal
  • Agostina Stradella
  • Marta Pineda Riu
  • Alexandre Teule Vega
  • Laura Valle Velasco
  • Barbara Rivera Polo
CLINICAL RESEARCHERS
  • Matilde Navarro Garcia
POSTDOCTORAL RESEARCHERS (R2)
  • Noemi González Abuín
  • Jesus Del Valle Dominguez
  • Mireia Morell Ginesta
  • Maria Lidia Feliubadalo Elorza
  • Julia Canet Hermida
  • Anna Fernandez Robles
  • Pilar Mur Molina
  • Juana Fernandez Rodriguez
  • Mariona Terradas Ill
  • Gardenia Vargas Parra
  • Sara Crespo Yanguas
  • Fatima Marin Nieto
PREDOCTORAL RESEARCHERS (R1)
  • Elsa Ezquerro Marrodán
  • Jose Marcos Moreno Cabrera
  • Paula Rofes Terrón
  • Núria Dueñas Cid
  • Isabel Quintana Gallardo
  • Edgar Creus Bachiller
  • María Isabel González Acosta
SCIENTIFIC SUPPORT
  • Gemma Aiza Buscarons
  • Elisabet Munte Roca
  • Hyerim Han
MANAGEMENT SUPPORT
  • Iolanda Rubio Carre
Cancer
Oncobell

Scientific production

63

PAPERS

20 PUBLICATIONS IN FIRST DECILE

47 PUBLICATIONS IN FIRST QUARTILE

Selected publications

  • Terradas M, Mur P, Belhadj S, Woodward ER, Burghel GJ, Munoz-Torres PM, Quintana I, Navarro M, Brunet J, Lazaro C, Pineda M, Moreno V, Capella G, Evans DGR, Valle L . TP53, a gene for colorectal cancer predisposition in the absence of Li-Fraumeni-associated phenotypes. GUT. 10.1136/gutjnl-2020-321825
  • Mur, Pilar; Garcia-Mulero, Sandra; del Valle, Jesus; Magraner-Pardo, Lorena; Vidal, August; Pineda, Marta; Cinnirella, Giacomo; Martin-Ramos, Edgar; Pons, Tirso; Lopez-Doriga, Adriana; Belhadj, Sami; Feliubadalo, Lidia; Munoz-Torres, Pau M.; Navarro, Matilde; Grau, Elia; Darder, Esther; Llort, Gemma; Sanz, Judit; Ramon y Cajal, Teresa; Balmana, Judith; Brunet, Joan; Moreno, Victor; Piulats, Josep M.; Matias-Guiu, Xavier; Sanz-Pamplona, Rebeca; Aligue, Rosa; Capella, Gabriel; Lazaro, Conxi; Valle, Laura. Role of POLE and POLD1 in familial cancer. GENETICS IN MEDICINE. 10.1038/s41436-020-0922-2
  • Stradella, Agostina; del Valle, Jesus; Rofes, Paula; Vargas-Parra, Gardenia; Salinas, Monica; Gonzalez, Sara; Montes, Eva; Lopez-Doriga, Adriana; Gomez, Carolina; de Cid, Rafael; Darder, Esther; Teule, Alex; Solanes, Ares; Munte, Elisabet; Capella, Gabriel; Pineda, Marta; Feliubadalo, Lidia; Brunet, Joan; Lazaro, Conxi. ERCC3, a new ovarian cancer susceptibility gene?. EUROPEAN JOURNAL OF CANCER. 10.1016/j.ejca.2020.09.023
  • Fernandez-Rodriguez, Juana; Morales La Madrid, Andres; Gel, Bernat; Castaneda Heredia, Alicia; Salvador, Hector; Martinez-Iniesta, Maria; Moutinho, Catia; Morata, Jordi; Heyn, Holger; Blanco, Ignacio; Creus-Bachiller, Edgar; Capella, Gabriel; Farre, Lourdes; Vidal, August; Soldado, Francisco; Krauel, Lucas; Sunol, Mariona; Serra, Eduard; Villanueva, Alberto; Lazaro, Conxi. Use of patient derived orthotopic xenograft models for real-time therapy guidance in a pediatric sporadic malignant peripheral nerve sheath tumor. THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY. 10.1177/1758835920929579
  • Damaso, Estela; Gonzalez-Acosta, Maribel; Vargas-Parra, Gardenia; Navarro, Matilde; Balmana, Judith; Ramon y Cajal, Teresa; Tuset, Noemi; Thompson, Bryony A.; Marin, Fatima; Fernandez, Anna; Gomez, Carolina; Velasco, Angela; Solanes, Ares; Iglesias, Silvia; Urgel, Gisela; Lopez, Consol; del Valle, Jesus; Campos, Olga; Santacana, Maria; Matias-Guiu, Xavier; Lazaro, Conxi; Valle, Laura; Brunet, Joan; Pineda, Marta; Capella, Gabriel. Comprehensive Constitutional Genetic and Epigenetic Characterization of Lynch-Like Individuals. CANCERS. 10.3390/cancers12071799

Research highlights

PROJECTS

23 Ongoing projects
9 Granted projects 

 

23 Ongoing clinical trial
8 Started clinical trials

PUBLISHED WORKS

3 Clinical guideline

8 Ongoing theses

Selected projects

  • Modelando el precancer en la deficiencia reparadora de apareamientos erróneos germinal para un seguimiento personalizado basado en la respuesta immune (2020 – 2024) PI: CAPELLA MUNAR, GABRIEL (IP) & PINEDA RIU, MARTA (co-IP). Funder: MEC-MINISTERIO EDUCACION I CIENCIA.
  • Postdoctoral Junior Leader – INCOMING (2019 – 2022) PI: CAPELLA MUNAR, GABRIEL. Funder: Fundació “La Caixa”.
  • Mecanismos no convencionales de inactivación génica en cáncer colorrectal hereditario (2016 – 2020) PI: VALLE VELASCO, LAURA. Funder: MINISTERIO DE EDUCACION Y CIENCIA.
  • Tackling current challenges in the genetic diagnosis of hereditary cancer through integrative analysis of molecular, clinical and population data (2020 – 2022) PI: LAZARO GARCIA, CONCEPCION. Funder: FIS-Instituto de Salud Carlos III.
  • Caracterización Clínica y molecular de los tumores des estroma de los cordones sexuales de ovario (2021 – 2023) PI: RIVERA POLO, BARBARA. Funder: FIS-Instituto de Salud Carlos III.