Metabolism and cancer

George Thomas

PRINCIPAL INVESTIGATORS
  • Albert Tauler Girona
  • Antonio Gentilella
POSTDOCTORAL RESEARCHERS (R2)
  • Joffrey Pelletier
  • Caroline Mauvezin
  • Maria Teresa Rubio Lopez
PREDOCTORAL RESEARCHERS (R1)
  • Ana Domostegui Fernandez
  • Flavia Iannizzotto
  • Carolina Martínez Herráez
SCIENTIFIC SUPPORT
  • Marta Garcia Cajide
  • Pau Bosch Crespo
Cancer
Oncobell

Scientific production

3

PAPERS

Impact factor: 29,548

2 PUBLICATIONS IN FIRST DECILE

*Average Journal IF

3 PUBLICATIONS IN FIRST QUARTILE

Selected publications

  • Pelletier, Joffrey; Riano-Canalia, Ferran; Almacellas, Eugenia; Mauvezin, Caroline; Samino, Sara; Feu, Sonia; Menoyo, Sandra; Domostegui, Ana; Garcia-Cajide, Marta; Salazar, Ramon; Cortes, Constanza; Marcos, Ricard; Tauler, Albert; Yanes, Oscar; Agell, Neus; Kozma, Sara C.; Gentilella, Antonio; Thomas, George. Nucleotide depletion reveals the impaired ribosome biogenesis checkpoint as a barrier against DNA damage. EMBO JOURNAL. 10.15252/embj.2019103838
  • Kusnadi, Eric P.; Trigos, Anna S.; Cullinane, Carleen; Goode, David L.; Larsson, Ola; Devlin, Jennifer R.; Chan, Keefe T.; De Souza, David P.; McConville, Malcolm J.; McArthur, Grant A.; Thomas, George; Sanij, Elaine; Poortinga, Gretchen; Hannan, Ross D.; Hannan, Katherine M.; Kang, Jian; Pearson, Richard B.. Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis. EMBO JOURNAL. 10.15252/embj.2020105111
  • Almacellas, Eugenia; Pelletier, Joffrey; Day, Charles; Ambrosio, Santiago; Tauler, Albert; Mauvezin, Caroline. Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instability. AUTOPHAGY. 10.1080/15548627.2020.1764727

Research highlights

PROJECTS

8 Ongoing projects
1 Granted projects 

PUBLISHED WORKS

2 Ongoing theses

Selected projects

  • Overcoming resistance to therapy in Colorectal Cancer by attacking the 40S-LARP1-5’TOPs anabolic reservoir (2020 – 2023) PI: GENTILELLA , ANTONIO. Funder: ASOCIACION ESPAÑOLA CONTRA EL CANCER.
  • Papel de los complejos 40S-LARP1 y IRBC en el cancer colorectal dirigido por c-myc. (2018 – 2020) PI: GENTILELLA , ANTONIO. Funder: MINISTERIO DE EDUCACION Y CIENCIA.
  • Ayudas para contratos predoctorales para la formación de doctores 2018 (2019 – 2023) PI: GENTILELLA , ANTONIO. Funder: MINISTERIO DE EDUCACION Y CIENCIA.
  • Laboratory of Cancer Metabolism (LMC) (2018 – 2020) PI: GENTILELLA , ANTONIO. Funder: AGAUR-GENERAL.CATALUNYA.
  • New therapeutic strategies for resistant colorectal cancer (2015 – 2020) PI: THOMAS , GEORGE. Funder: ASOCIACION ESPAÑOLA CONTRA EL CANCER.