Hepato-biliary-pancreatic pathology

Jose Castellote Alonso

PRINCIPAL INVESTIGATORS
  • Joan Berenguer Gornals Soler
  • Juli Busquets Barenys
  • Joan Fabregat Prous
  • Emili Ramos Rubio
  • Carme Baliellas Comellas
  • Laura Llado Garriga
CLINICAL RESEARCHERS
  • Rosa Rota Roca
  • Teresa Serrano Pinol
  • Jaume Torras Torra
  • Antoni Rafecas Renau
  • Sandra Maisterra Santos
  • Sandra Ruiz Osuna
  • Nuria Pelaez Serra
  • Luis Secanella Medayo
  • Francesc Bas Cutrina
  • Albert Garcia Sumalla
PREDOCTORAL RESEARCHER (R1)
  • Julio Guillermo Velásquez Rodríguez
Translational Medicine
Digestive system, diagnostics, pharmacogenetics, care support and clinical prevention

Scientific production

26

PAPERS

Impact factor: 140,952

7 PUBLICATIONS IN FIRST DECILE

11 PUBLICATIONS IN FIRST QUARTILE

Selected publications

  • Colán-Hernández J, Sendino O, Loras C, Pardo A, Gornals JB, Concepción M, Sánchez-Montes C, Murzi M, Andujar X, Velasquez-Rodriguez J, Rodriguez de Miguel C, Fernández-Esparrach G, Ginés A, Guarner-Argente C . Antibiotic Prophylaxis Is Not Required for Endoscopic Ultrasonography-Guided Fine-Needle Aspiration of Pancreatic Cystic Lesions, Based on a Randomized Trial. GASTROENTEROLOGY. 10.1053/j.gastro.2020.01.025
  • Trebicka, Jonel; Gu, Wenyi; Ibanez-Samaniego, Luis; Hernandez-Gea, Virginia; Pitarch, Carla; Garcia, Elisabet; Procopet, Bogdan; Giraldez, Alvaro; Amitrano, Lucio; Villanueva, Candid; Thabut, Dominique; Silva-Junior, Gilberto, Jr.; Martinez, Javier; Genesc, Joan; Bureau, Cristophe; Llop, Elba; Laleman, Wim; Palazon, Jose Maria; Castellote, Jose; Rodrigues, Susanag; Gluud, Liselotte; Ferreira, Carlos Noronha; Barcelo, Rafael; Canete, Nuria; Rodriguez, Manuel; Ferlitsch, Arnulf; Mundi, Jose Luis; Gronbaek, Henning; Hernandez-Guerra, Manuel; Sassatelli, Romano; Dell’Era, Alessandra; Senzolo, Marco; Abraldes, Juan G.; Romero-Gomez, Manuel; Zipprich, Alexander; Casas, Meritxell; Masnou, Helena; Primignani, Massimo; Weiss, Emmanuel; Catalina, Maria-Vega; Erasmus, Hans-Peter; Uschner, Frank Erhard; Schulz, Martin; Brol, Maximilian J.; Praktiknjo, Michael; Chang, Johannes; Krag, Aleksander; Nevens, Frederik; Calleja, Jose Luis; Robic, Marie Angele; Conejo, Irene; Albillos, Agustin; Rudler, Marika; Alvarado, Edilmar; Guardascione, Maria Anna; Tantau, Marcel; Bosch, Jaime; Torres, Ferran; Pavesi, Marco; Garcia-Pagan, Juan Carlos; Jansen, Christian; Banares, Rafael. Rebleeding and mortality risk are increased by ACLF but reduced by pre-emptive TIPS. JOURNAL OF HEPATOLOGY. 10.1016/j.jhep.2020.04.024
  • Latacz E, van Dam PJ, Vanhove C, Llado L, Descamps B, Ruiz N, Joye I, Grünhagen D, Van Laere S, Dirix P, Mollevi DG, Verhoef C, Dirix L, Vermeulen P . Can medical imaging identify the histopathological growth patterns of liver metastases?. SEMINARS IN CANCER BIOLOGY. 10.1016/j.semcancer.2020.07.002
  • Pommergaard, Hans-Christian; Rostved, Andreas Arendtsen; Adam, Rene; Rasmussen, Allan; Salizzoni, Mauro; Gomez Bravo, Miguel Angel; Cherqui, Daniel; De Simone, Paolo; Houssel-Debry, Pauline; Mazzaferro, Vincenzo; Soubrane, Olivier; Carlos Garcia-Valdecasas, Juan; Fabregat Prous, Joan; Pinna, Antonio D.; O’Grady, John; Karam, Vincent; Duvoux, Christophe; Thygesen, Lau Caspar. Mortality after Transplantation for Hepatocellular Carcinoma: A Study from the European Liver Transplant Registry. LIVER CANCER. 10.1159/000507397
  • Duenas, Eva; Cachero, Alba; Amador, Alberto; Rota, Rosa; Salord, Silvia; Gornals, Joan; Xiol, Xavier; Castellote, Jose. Ulcer bleeding after band ligation of esophageal varices: Risk factors and prognosis. DIGESTIVE AND LIVER DISEASE. 10.1016/j.dld.2019.06.019

Research highlights

PROJECTS

2 Ongoing projects
1 Granted project

 

7 Ongoing clinical trials

PUBLISHED WORKS

2 Ongoing theses

2 Clinical guidelines

Selected projects

  • Estudio multicéntrico, aleatorizado, abierto y de 12 meses de duración de la seguridad, eficacia, farmacocinética (PK) y farmacodinámica (PD) de dos pautas posológicas del anticuerpo nonoclonal anti-CD40, CFZ533, frente al tratamiento estándar en receptores adultos de traasplante hepático de novo con un seguimineto adicional de 12 meses (CONTRAIL I) (2019 – 2025) PI: LLADO GARRIGA, LAURA. Funder ref.: CCFZ533A2202.
  • Estudio para el desarrollo y validación de una huella genética para el diagnóstico de cáncer de páncreas y lesiones precursoras (2017 – 2026) PI: FABREGAT PROUS, JOAN. Funder: Advanced Marker Discovery, S.L..
  • An open-label study to evaluate safety, efficacy and pharmacokinetics (PK) of Patisiran-LNP in patients with hereditary transthyretin-mediated amyloidosis (HATTR amyloidosis) with disease progression post-orthotopic liver transplant (2019 – 2025) PI: LLADO GARRIGA, LAURA. Funder ref.: ALN-TTR02-008.
  • A phase 2, double-blind, randomized, parallel-group study evaluating the efficacy, safety, and tolerability of obeticholic acid, administered alone or in combination with bezafibrate, in subjects with primary biliary cholangitis who had an inadequate response or who were unable to tolerate ursodeoxycholic acid (2019 – 2020) PI: CASTELLOTE ALONSO, JOSE. Funder ref.: 747-213.
  • Estudio clínico multicéntrico de fase II para evaluar la seguridad y la eficacia preliminar de dos regímenes posológicos de Hepastem en pacientes coninsuficiencia hepática crónica agudizada. (2018 – 2020) PI: CASTELLOTE ALONSO, JOSE. Funder ref.: HEP101.